Friday, October 2, 2015
every cell in your body has a potentially (likely?) unique genome
Science | Every cell of your body was generated by cell division, forming a lineage tree that goes back to the fertilized egg. Mutations are introduced by errors in DNA replication at every cell division, as well as by mutational processes that operate continuously, such as exposure to ultraviolet light. As a consequence, every cell may have its own unique genome, with potentially distinct gains and losses of function. Furthermore, these mutations create a record of the developmental ancestry of each cell, which can be used to reconstruct their lineage tree.