a way to quietly get rid of the no longer fit?

npr | Medical Errors Are No. 3 Cause Of U.S Deaths, Researchers Say

A study by researchers at Johns Hopkins Medicine says medical errors should rank as the third leading cause of death in the United States — and highlights how shortcomings in tracking vital statistics may hinder research and keep the problem out of the public eye.

The authors, led by Johns Hopkins surgeon Dr. Martin Makary, call for changes in death certificates to better tabulate fatal lapses in care. In an open letter, they urge the Centers for Disease Control and Prevention to immediately add medical errors to its annual list reporting the top causes of death.

Based on an analysis of prior research, the Johns Hopkins study estimates that more than 250,000 Americans die each year from medical errors. On the CDC's official list, that would rank just behind heart disease and cancer, which each took about 600,000 lives in 2014, and in front of respiratory disease, which caused about 150,000 deaths.

Medical mistakes that can lead to death range from surgical complications that go unrecognized to mix-ups with the doses or types of medications patients receive.

But no one knows the exact toll taken by medical errors. In significant part, that's because the coding system used by CDC to record death certificate data doesn't capture things like communication breakdowns, diagnostic errors and poor judgment that cost lives, the study says.

genetic ENGINEERING (not just theory) to reverse aging

GeekWire | BioViva’s Liz Parrish makes progress in controversial gene quest to reverse aging

The way BioViva founder Elizabeth Parrish sees it, biological aging is a disease – and she’s willing to bet her life on a cure.

Last fall, the 45-year-old Seattle-area woman underwent an experimental type of gene therapy aimed at addressing some of the big effects of aging, including loss of muscle mass and a shortening of the chromosomes’ telomeres. The procedure was reportedly done in Colombia, to get around U.S. regulations.

The idea of having gene therapy done on yourself raised eyebrows in the biotech community, but Parrish was unfazed.

“I 100 percent believe that it will work, or else I wouldn’t have done it,” Parrish told GeekWire during an interview in February. “I didn’t try to flame out in glory. The research shows that it should absolutely work.”

Now BioViva is reporting that it does seem to work, at least on Parrish’s telomeres. And that’s likely to fuel a debate over the widening scientific quest for greater longevity – conducted not only by BioViva, but by other ventures such as Human Longevity Inc. This week, Human Longevity announced a 10-year deal with AstraZeneca to analyze 500,000 DNA samples for anti-aging clues.

the contraction is coming

Reuters | Leading global coal miner Peabody files for bankruptcy

Leading global coal producer Peabody Energy Corp BTU.N filed for U.S. bankruptcy protection on Wednesday after a sharp drop in coal prices left it unable to service debt of $10.1 billion, much of it incurred for an expansion into Australia.

The Chapter 11 bankruptcy filing ranks among the largest in the commodities sector since energy and metal prices began to fall in mid-2014 as once fast-growing markets including China and Brazil started to slow.

the SMART way to downsize your population in the coming contraction

Vox | Japan's demographic time bomb, in one chart
Japan has a major demographic problem: 26 percent of its population is elderly, the largest percent of any country in the world. That's because Japan's birthrate is declining, as is its overall population. In other words, a huge chunk of its population is getting old and leaving the workforce, and not enough people are being born to take their place.

butter not bad for the heart, stay AWAY from vegetable oil!

The BMJ | Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)

Abstract

Objective To examine the traditional diet-heart hypothesis through recovery and analysis of previously unpublished data from the Minnesota Coronary Experiment (MCE) and to put findings in the context of existing diet-heart randomized controlled trials through a systematic review and meta-analysis.

Design The MCE (1968-73) is a double blind randomized controlled trial designed to test whether replacement of saturated fat with vegetable oil rich in linoleic acid reduces coronary heart disease and death by lowering serum cholesterol. Recovered MCE unpublished documents and raw data were analyzed according to hypotheses prespecified by original investigators. Further, a systematic review and meta-analyses of randomized controlled trials that lowered serum cholesterol by providing vegetable oil rich in linoleic acid in place of saturated fat without confounding by concomitant interventions was conducted.

Setting One nursing home and six state mental hospitals in Minnesota, United States.

Participants Unpublished documents with completed analyses for the randomized cohort of 9423 women and men aged 20-97; longitudinal data on serum cholesterol for the 2355 participants exposed to the study diets for a year or more; 149 completed autopsy files.

Interventions Serum cholesterol lowering diet that replaced saturated fat with linoleic acid (from corn oil and corn oil polyunsaturated margarine). Control diet was high in saturated fat from animal fats, common margarines, and shortenings.

Main outcome measures Death from all causes; association between changes in serum cholesterol and death; and coronary atherosclerosis and myocardial infarcts detected at autopsy.

Results The intervention group had significant reduction in serum cholesterol compared with controls (mean change from baseline −13.8% v −1.0%; P<0.001). Kaplan Meier graphs showed no mortality benefit for the intervention group in the full randomized cohort or for any prespecified subgroup. There was a 22% higher risk of death for each 30 mg/dL (0.78 mmol/L) reduction in serum cholesterol in covariate adjusted Cox regression models (hazard ratio 1.22, 95% confidence interval 1.14 to 1.32; P<0.001). There was no evidence of benefit in the intervention group for coronary atherosclerosis or myocardial infarcts. Systematic review identified five randomized controlled trials for inclusion (n=10 808). In meta-analyses, these cholesterol lowering interventions showed no evidence of benefit on mortality from coronary heart disease (1.13, 0.83 to 1.54) or all cause mortality (1.07, 0.90 to 1.27).

Conclusions Available evidence from randomized controlled trials shows that replacement of saturated fat in the diet with linoleic acid effectively lowers serum cholesterol but does not support the hypothesis that this translates to a lower risk of death from coronary heart disease or all causes. Findings from the Minnesota Coronary Experiment add to growing evidence that incomplete publication has contributed to overestimation of the benefits of replacing saturated fat with vegetable oils rich in linoleic acid.

can i take him with me to a bar to help me pick-up women?

Hot Hardware | IBM's Watson Cognitive AI Platform Evolves, Senses Feelings And Dances Gangnam Style At NVIDIA GTC

What has Watson been up to since then? IBM has focused its efforts on more practical applications for Watson, including services that are used by doctors, lawyers, and other professionals that need to analyze massive amounts of data. The challenge IBM faces is keeping Watson fresh, with the world's devices producing some 2.5 exabytes of data every day that is expected to blow-up to 44 zettabytes by the year 2020. To keep up with the information overload, IBM announced late last year that it was adding NVIDIA's Tesla K80 processing engines to the mix. Those high performance compute GPUs are playing a key role in Watson's cognitive computing development, especially in terms of natural language processing capabilities. 

The result? Watson is more capable and human-like than ever before, especially when injected into a robot body. We got to see this first-hand at NVIDIA's GPU Technology Conference (GTC) when Rob High, an IBM fellow, vice president, and chief technology officer for Watson, introduced attendees to a robot powered by Watson. During the demonstration, we saw Watson in robot form respond to queries just like a human would, using not only speech but movement as well. When Watson's dancing skills were called into question, the robot responded by showing off its Gangnam Style moves.

This is the next level of cognitive computing that's beginning to take shape now, both in terms of what Watson can do when given the proper form, and what it can sense. Just like a real person, the underlying AI can get a read on people through movement and cognitive analysis of their speech. It can determine mood, tone, inflection, and so forth.

considering the current state of shipping, what exactly would these drone ships carry?

The Telegraph | Crewless 'drone ships' will be sailing the seas by 2020

Remote-controlled “drone ships” will be plying the sealanes without crews on board by the end of the decade, according to Rolls-Royce.

The FTSE 100 company best known for its aircraft engines is heading a consortium working to develop the technology needed for ships controlled from land bases, making them cheaper to run.   

“This is happening. It’s not a question of if, it’s a question of when,” said Oskar Levander, head of innovation for Rolls’s marine unit. “We will see a remote controlled ship in commercial use by the end of the decade.”

He predicted the system could turn ships into a seaborne version of car service Uber, with the potential to radically change the current shipping sector.

“Drone ships will allow the creation of new services, which will support existing players to make their businesses more efficient and enable new entrants with new business models to the sector, with a potentially similarly disruptive effect to that caused by Uber, Spotify and Airbnb in other industries.”